Crazy though! The scene between Mary Jane and Felicia, plus the cover of the next issue, made me think.
Symbiotes can "absorb" the personalities of one host and "download it" in another host, as Scream has done recently giving her current host (Andi) the personalities of its past hosts. So, how about if one symbiote "drains" Felicia and "downloads" her in MJ's mind. Sounds crazy, I know, but in a What If's story we must expect ANYTHING.
Funny enough, that was pretty much exactly what happened with Carnage and Cletus Kasady, with Kasady's personality imprinted onto the Carnage symbiote attempting to dominate any subsequent host the Carnage symbiote bonded with, most recently Kasady's archenemy Eddie Brock back in the post-Absolute Carnage arc of Venom called Venom Island.
The spider is always on the hunt.
I know, right?
Whatever is going to happen next, pretty sure the symbiote will want to be with Peter again. And knowing how much he cares for Mary Jane and Black Cat, he could do something like "merging them togather" to make them happy. As having the powers of Black Cat, Mary Jane could protect herself or something. (Crazy, but I don't see it as impossible).