A good plot for the next arc would be the birth of the "Spider-Family". You know, Peter Parker was the first spider, so it would be fitting for him to have a role on the creation of the other spiders: Jessica Drew, Madame Web (Cassandra Webb), Gwen Stacy?, Miles Morales, Anya Corazon... You get the idea.
It seems my theory was right according to this new:
https://www.cbr.com/marvel-kevin-fei...men-mcu-canon/