The problem with One More Day was that it was never designed to be good. It was designed to essentially be a soft reboot, ending the Marriage because Marvel saw it as a problem that was inherited during the late 80's.

I've noticed around this time there was this nasty snark in the underbelly of Spider-man stories.
Peter would laugh and say "I'm too young to get married" which may just be a reference to the fact that editorial have historically been against the marriage.
It only seems with Spencer, do you have a genuine attempt to address OMD. Last Remains was an entire arc that almost felt like it was a loose conclusion to the three part arc of One More Day and One Moment in Time with it heavily implying the deal was wrong.
I think Marvel have regrets over how they handled it, but I don't think they regret getting rid of the marriage. It's a problem that the newer editorial have now inherited.
For the most part, a lot of the big names during that era in terms of both editing and writing have left, with only Nick Lowe and Dan Slott still being around at Marvel, and Slott is so far away from Spider-man at this point that he doesn't have any input on the comics at all (I know there are other editors, but they've had nothing to do with Spider-man and do their own thing).
Quesada is still with Marvel in a limited capacity and the rest have either moved on or in different sections of the company.
However, Marvel is a very different company now to what it was in 2007 and we have to face the facts, the marriage lasted about 20 years, One More Day happened about 15 years ago and People are still talking about it.
Peter hitting MJ during the Clone Saga never gets talked about but Hank Pym hitting Janet does.
MJ smoking never gets talked about because it was just a stupid way to split them up.

I've said before, I'm okay with them splitting up, hell, they could have waited 5 years and split them up after Superior. The trouble was how they did it, and I think the writers understand that.

There's a reason why Spencer's run starts with "To have and to hold" and it's not just because that's a good deep cut reference, but because that comic was actually saying it was against One More Day.
The issue with Mary-Jane was that Marvel didn't really like her, but the fans did. So you have this awkward situation where you have to keep the fans happy but the writers and editors remain unhappy. At least that's what it was like in the 90's. By the 2000's, it was just a few People gunning for their marriage to end and those were the vocal, powerful groups.

Quesada's time as Editor in Chief will be remembered for his hand in One More Day, not that Marvel during his tenure was actually pretty good. It was the last big he did and is ultimately his legacy.
The problem with Dan Slott wasn't that his work was bad, once he got Amazing to himself, he was great, and I enjoyed Superior as well, but it was that he played into the snarky group while the other writers just wanted to tell their stories.
He basically joined in with the laughing at the audience during those early stories. "Oh there is a mugger, I should stop him as Spider-Man, but no I shouldn't because I don't want Jonah to sell papers".
That first Brand New Day arc left a worse impression on me than One More Day as instead of continuing with grace, it was snarky comments about a Peter Parker that doesn't exist.

Nowadays, the time has changed a lot. Slott left Amazing almost immediately after Alonso left, which leaves me to believe one of two things, he was taken off the book or he jumped off for the big company relaunch.

I do want to point out however how funny it is that Marvel wanted Spider-man to be young, especially as Ultimate Spider-man was coming out at that time and did everything that Marvel wanted Spider-man to be.
In fact, it did things better