World War Maggia

Joseph Manfredi, new head of the Silvermane family, the Rose, taking over his father’s criminal enterprise, Mister Negative, Hammerhead, Madame Masque, and Bushmaster are gathered together on Madripoor from a mysterious new Crime Master, who instead of heading a family, is offering two new designer drugs, one of which will grant those who survive with superhuman gifts, and the other makes you a sleeper agent, to transform into a goblin-esque type of character. Turns out the new Crime Master is the post OMD Harry Osborn, who cracked mentally after being tortured by the Kindred.