Depends entirely on who it is. For instance, going back a ways, I always thought Bill Bixby was a very good actor, especially when you saw scenes and roles that showed it. There was even an Emmy nomination. But he got typecast into what were considered fluff shows. In fact, that was Hugh Jackman's comment on Bixby, a great actor trapped in roles people considered fluff.
Again, it all comes down to the specific actor we are talking about.