Nope. Anything new will just be the nature of the character himself, but it won't stray from what we've seen before from the MCU. There'll be surprises, it'll probably be good, but it'll stay within the lines. The MCU is reliable and consistent in those regards. You can enjoy it, I do, but if you want different you have to look elsewhere.
Even if you go back at look at Rob's Deadpool stuff, he was a wisecracking joker that never shut up and annoyed people. The very first time Deadpool was defeated by Cable, Cable packed him up in a crate and mailed him back home. That's pretty much exactly the same kind of stuff you see from the character today.
Still, Rob wasn't exactly the best comedy writer but the start was still there. It's just later writers kept making him wackier and wackier.
Steve Ditko's Spider-man is hardly the same guy we see nowadays but nobody wants to take the credit from him.