I suppose your right to an extant...
I was thinking about propelling Vic Sage to another Question run (all we got was Rick Veitche's dreadful mini series), but then again, not one Charlton character got a second run.
Greg Rucka would also pick up where Denny O Neil left off, and the Question would have a significant impact on the development of the Huntress, which would spin off to the Question being featured on the Justice League Unlimited series.
I suppose by least notable, I'm thinking forgotten. Unless your a DC martial artist guru, it doesn't get cited a lot.