"No" is the obviously wrong answer here. There's been great work about politics and social issues in every medium. To deny that possibility in the future is absurd.

There is a time and place for it, though. Sesame Street would not be the right place to tackle the Texas abortion legislation.

One of the messy things in politics is that some people just can't accept that decent humans hold different views, and would take advantage of the writer's ability to put a foot on the scale, and make outcomes match their policy preferences in a way that doesn't match with real life. There is always a potential for backlash as the people who make art tend to have different views from the average voters, which has implications for arts funding and can provide an opportunity for populist demagogues to rally against popular culture. The space to tackle complicated questions is also quite finite, so that's definitely something people should keep in mind when tackling politics in a five minute song or a twenty page comic book.

This question gets into branding a bit. Some series develop followings, and it can be upsetting for viewers if a new voice differs from what they've seen before. It'd be weird if a standard cop drama were suddenly written by someone who believes ACAB and that police abolition is necessary. Likewise, it would be strange if Captain Planet were written by libertarians trying to show the tradeoffs to environmental legislation. Meanwhile, more experimental work can encourage activism and be much more radical.

The important thing would be that the writers and artists play fair, although that is very much in the eye of the beholder.