Maybe this will answer the question: The demand is not there. According to Wikipedia Spider-Man loves Mary Jane only lasted 20 issues ( it was released in trades)), which tells you that girls back then did not buy enough issues of the comic to justify it going further and women of today are not asking for it ( either for nostalgic purposes, to share with their daughters or both). Of a more recent vintage the Original Gwen comic that was interrupted due to COVID still has not come out with the final issues: In print, digital or trades. Why? Quite likely the same reason: Demand is not there.