With the spell I am under the impression that every Spider-Man did previously in the MCU still happened ( Civil War, Homecoming, Infinity War, Endgame, Far From Home) with the tweak that no one knew Spider-Man’s identity. He definitely isn’t removed from the MCU but the movie places him in a more traditional Spider Man status. Broke, crappy apartment, homemade suit and tech, his identity hidden, and him just fighting street level crime in NYC.