Haven't read Dragon Age yet, Mass Effect was just kinda meh for me. I think most of the stories came out during Mass Effect 2 and in between that and 3, so they couldn't do any "real" stories, so it's basically a buncha made up characters and the Illusive Man (who I've never really cared for, it all wound up being too try-hard to make you feel bad for him or whatever). And the origin issues I just didn't care for. It's just all kinda forgettable, not really bad, it definitely could have been worse.
I'm hoping that now that the original trilogy of games is over they can do better story-wise since the characters aren't locked in for games anymore (in theory). The first issue of Foundations looked like it was on the right foot. I'm hoping that since it's 13 issues that it'll get the Library or some kind of HC treatment when it's through.