In recent years the Spider-Man franchise has taken to becoming a more diverse and inclusive franchise beyond Peter Parker. The theme is that anyone could put on the mask.
It's important to note that Spider-Man is a big deal. The biggest deal in Marvel. But there is still one group that has never truly gotten representation under the Spider name. And that is the LGBTQ community.
Not a single major Spider is canonically LGBTQ. Not one who has headlined their own title.
Now, you might say "there have been LGBTQ Spiders before" and this is true. But they weren't what I would call a major character. The closest would be Ultimate Jessica Drew. She never had her own title where she was the headline star. She hasn't appeared in years. And she will always be secondary to the original Jessica Drew. (She was also a female clone of Ultimate Peter Parker, which opens up a whole can of worms.)
That can't be it, you must be thinking. And it isn't. There was an LGBTQ Spider-MJ introduced in Exiles. She never joined the team and only showed up for a few issues. And then she was killed rather unceremoniously in Spider-Verse.
And I think that might be it. There are other LGBTQ characters in Spider-Man comics like Black Cat, but they aren't a Spider. They don't bare the moniker of "Spider." This is far too short. This is something that must be corrected.