Humans/marvel 616
1,000,000 BC
Aesheim burning
...
Homo erectus
One million years ago, "The "evolutionary borderline between apes and humans" existed.under the form of Homo erectus. The two pre-human spawned a tribe over the centuries, the Wanderers, that had their leader and its mate to return each year (in the course of the tribe's migration) to the Garden.
First modern men and mutants
Around that time, while most men communicated with grunts, smarter individuals using articulated languages began to sprung, such as those who became known as Ghost Rider and Wendigo.
At the same period, Agamotto mentioned mutants,presumably referencing Lady Phoenix.
First Host, Deviants, Eternals and origin of the Mutants
After weeks of experiments, the last subjects of Oneg were released and the Celestials left the planet