Although I was a huge fan of the show in it's day, they got very lucky to find a bodybuilder with both the height and muscle mass of Lou Ferrigno. Even at that, it had its weaknesses. What killed a She-Hulk series back then (and they did screen testing for it) was that they could not find any woman who had both the muscularity and the sheer height.
If She-Hulk was done on a farcical level, a live action version might work as part of the joke. Other than that, there was no chance. I think it's more just a fun debate about what woman could possibly pull it off.