In Joe Quesada's letter announcing his departure from Marvel, he talks about still having plans to contribute to Marvel, and ends by promising that his next crazy adventure will be amazing. I've heard some speculation that he wants to do something Spider-Man related, and he had hinted about wanting to do a third story after One More Day and One Moment in Time.
It's entirely possible that Marvel doesn't want to do this, and he doesn't want to devote months, if not more, of creative energy to making a TPB-length Spider-Man story.
But should he?
This is an idea he's had for a while.
The choices for the poll are going to be....
1) Yes- You want to see him tackle a One More Day related project.
2) No- You do not want to see him tackle a One More Day related project.
3) It depends- The story was supposed to be about something that changes as a result of One More Day. It may have nothing to do with the spider-marriage, or Mary Jane. So maybe you wouldn't want to see him tackle some potential story ideas, but there's stuff he may plausibly touch on that you wouldn't mind seeing him handle.