Just thinking about comic sales. And an aging audience. Now there are tons of other things that could be done, and I don't really want this thread to be about suggestions on new characters, etc. This is specifically about structure and audience.
You know, one issue, one story (possibly more than one story per issue, as that was common). I'm not saying there couldn't be any aging or character progression over years, or that marriage, babies, job changes or divorces couldn't happen. Though it could similarly be a Simpsons/Ducktales, etc. sort of thing where no one ages. The point is the idea of putting your general monthly comics in Walmarts and Rite-aids and and so on and making it easy for a person (especially a kid) to pick up an issue and get a story that has a beginning, middle, and end and they don't have to buy next month's issue to find out what happens and they can read only one out of every four issues and not be confused. To make it casual reading for a broad audience again.
I can't say that I really believe it would work - that method was failing when they went away from it. And there's so much more competition for entertainment now. And comics are more expensive. But this open-ended comics with multiple crossover and events is not very accessible for new readers. I love the ongoing universe, but I do have to admit that it can only go so many years before it collapses in on itself and retcons and inconsistencies make it messy and make a reboot (soft or hard) more desirable. And that number of years gets shorter and shorter with more big events that "change everything" and turn villains good and heroes bad. It's the worst of both words - a lack of accessibility for new readers and and old-time readers frustrated with no actual forward progression and established events and characterizations tossed out the window whenever it's convenient.
Obviously, all OGNs would be another approach to take, but I'm really talking about monthly comics in an open-ended universe and whether said model would stand any chance of success or just kill them more quickly because of hemorr*****g older readers and being unable to appeal to newer ones.