I'm curious how the MCU would tackle CW2 but I imagine them doing some version of Avengers vs Men instead.
Although having Riri deal with an enemy that could see the future would be cool.
Legacy villians do exist and they are a way to deconstruct legacy. People get angsty about sharing villians but sharing villian groups is fine. So having Kamala fight a rookie ninja of the hand is a cool way to develop a villian for her. It could get tiresome if repeated to often but it's worth exploring.