For myself, I think the point here is that it does have minimal effect - the words he uses. It's like him getting a cold, starting to get the sniffles, and then bouncing it and being fine. He's getting hollowed out, melted, changed to a completely different substance, none of which has any real kind of impact on him. He views this as 'minimal effect', and even while it's happening it's pretty clear he's meant to still be thinking, still piloting his chair (which is controlled by his mind, as I understand). It happens, but it doesn't stop him from doing whatever he's doing while it's happening, and it doesn't stick.
I get the point Nik is making - if this stuff is actually doing something, then speed steal will also do something - but I also feel the point the comic makes would then be 'Speed steal might work on him...but it won't stick', and it really won't stop him from just working through it, or his mind from continuing to do whatever (dude is changed to crystal or his brain is hollowed out and removed and he's continuing to fly his chair*).
* Only comics would have me say something so ridiculous-sounding, and yet so true.