Something I have been thinking about...and pushed the the forefront of my thoughts with the Kamala Inhuman/mutant twist...
How prevalent would Non-baseline human genes be in the general population?
Human, mutant, Inhuman, Atlantean, Eternal, Deviant, all the different pantheons (Asgardian, Olympian, etc...), mot to mention alien visitation...
How likely is it that a "normal human" in the 616 would have some genes from these other races from hundreds or thousands of years in the past?