I think it would make sense for Dr Poison from the Wonder Woman comics to have a kid. The version introduced Post Crisis by Eric Luke was already the grand daughter of the original Golden Age version. You could stretch that out even further; introduce a WW1 version of Dr Poison based on the 2017 movie who could be the mother of the Golden Age version, the original Golden Age version active during WW2, the Post Crisis version introduced by Eric Luke and is the grand daughter of the Golden Age version and you could go further to reveal that the Rucka version in Rebirth is actually a cousin or maybe sibling of the Post Crisis version. Then you could introduce a new Dr Poison who doesn't want to be a villain and break away from the 'family business'. Make them androgynous too since there are so few gender non conforming characters who aren't villains in WW comics.
The only one that doesn't really fit is the Nu52 version introduced during the Finch run who was Russian.