Much like 'Beast', 'Thing' is a title or name that is used in fiction. As noted by bigadventure, however, there is a standout example in Roger Zelazny's classic Creatures of Light and Darkness.
The Thing That Cries In The Night.
The Thing That Cries In The Night is a Lovecraftian-esque horror of enormous power* and indefinite, ever-changing form. It annihilates and consumes worlds. It obliterates beings to the point where galactic+ scale spiritual technology that can revive someone from the dead and control the Tides of Life and Death of what is vaguely noted as being the universe can only barely manage to keep a victim of The Thing intact as a disembodied spirit. The Thing endures a thousand years of torment by the equivalent of Reed Richards using all of the technology at his disposal (if Reed were also capable of creating technology that controlled spiritual matters as well, on a potentially universal scale) in an attempt to kill it, and the Thing still survives. It is struck by supernova-level energies in battle, and still continues. Its conflict with another being of power destroys the planet above which they battle (they're not even on the ground, they're duking it out high in the atmosphere and the planet comes apart). A weapon that destroys stars is employed against it, and that weapon does all of KO The Thing for a limited amount of time, just enough for it to be taken captive.
And so I pose the question: What THING (named or titled) can defeat The Thing That Cries In The Night?
* For those interested in spoilers, The Thing That Cries In The Night Is spoilers:end of spoilers Also, two threads from me in two days, a very odd feeling.
God. Big G, creator of the universe, etc, all that stuff. Diminished and wounded by the usurpation of some of its power, but God nonetheless.