Yeah, instead of Thor and Superman, err, Hyperion, Thanos is going to battle Hulk and Superman, err, Blue Marvel (as some see him as a Superman pastiche).
Do we really need to buy this issue to know how this ends?
Thor/Hulk = last man standing, but Thanos pretty much smokes them.
Hyperion/Blue Marvel = Get injured and take a knee.
Everyone else is just fodder.