Originally Posted by
JudicatorPrime
Doom has been trying to give himself powers for years. It stands to reason that either he has experimented on others before, or he has read at length some of the papers of other great scientists like the Enclave and the High Evolutionary, who have either created powerful beings, or turned themselves into very powerful beings through scientific means.
Let's not forget that Doom has created other superhuman beings, including Darkoth the Death Demon through a combination of mysticism and science. And then there's also Victorious, who, if memory serves, got her powers by virtue of the Power Cosmic experimentations that Doom performed on Silver Surfer and Terrax.