The synopsis says exactly where she's moving to. I assume this means they're finally having her graduate high school (which should've happened before Iman Vellani's minis, if you do the maths counting all the holidays and timeskips since her debut, her still being in school past that point requires her to be a year younger than originally stated when she debuted). Will she move to New York for college (Empire State University?) and that's why she's in Manhattan? If so, it's not just Miles she might run in to - Gwen's a student there as well, and isn't commuting back to Earth-65 any more.
Miles ought to be out of high school now as well - he and Kamala are both at least 18 if they were 16 when Secret Wars happened.