Yeah, I really wish we could see Otto get back at both Spider-norman and Mephisto for what they forced him to do (getting rid of his Spock persona), but sadly this wont likely happen, because..
1- Spider-norman is dead, having killed himself during the early stages of End of the Spiderverse
2- Mephisto seems basically untouchable (ask Peter), and after being Aaron's pet character during his avengers run, I dont see him seeing making another appearance any time soon