The writers keep pretending like they don't know what to do with Neal Shaara (like Monet said in X-Factor, which was pretty meta), when there are so many stories like attempting to redeem Karima sitting right there.
Having said that, the Brian Wood all-female Adjectiveless run did cure Karima completely and turn her into a regular human being... and then there wasn't much left to do with her. Giving in to villainy does work for her. It's just annoying that post-Hickman, it basically became the Sinister show, despite Inferno setting up so much for Omega Sentinel.