I think Eshu (the guy who bore the fire totem in the Vixen animated CW Seed "series" should be resurrected and brought over to the comics. Somehow he survived (like Kuasa) and once again gets his hands on the fire totem, He could be a recurring rogue for Vixen Maybe the Tattooed Man would also make a great rogue for her. Out of the Floronic Man, Floronic Woman or Poison Ivy to go up against Vixen, I'd rather have Poison Ivy. The frenemy dynamic between Vixen and Ivy is a good idea. Fauna Faust is also a good idea for a rogue, along with her father Felix (magical enemy).
Side question: Since Vixen can mimic natural abilities from other humans since they are also animals, does that mean she can theoretically channel the intellect of Mr. Terrific?