Well, they didn't reboot to bring back Iron Man, way back, or Loki, Odi, Human Torch, Spider-Man, Thor, Captain America, or Bucky.
One, a while after, or during, Siege. Two around Fear Itself or so, and another both in The Other: Evolve Or Die, and Superior Spider-Man #30.
No real need to start from scratch, or reconfigure the continuity of things, to bring back the Invisible Woman, especially when it wasn't done for her brother, or herself, many years back.
Sure, even went to Heaven to get Ben back, after Reed/Sue/Doom killed him, so are ways around things.
A divorce for Reed and Sue's the only thing that'd affect me, but one of the few couples to keep on lasting, to my knowledge.
To now. Peter and MJ didn't, Steve and Sharon I'm not sure about, nor Tony and Pepper.
Thor and Jane, no to a degree.
Or, Scott and Jean, T'Challa and Ororo, but believe Black Bolt and Medusa are still together, along with Luke and Jessica, and of course, Logan and Ororo aren't, but something's something.