I lot of people who like Spidey like Ms. Marvel, it seems. I'm not sure about the humor, as I don't read the book, but it's got lovely art by Adrian Alphona, who did Runaways, another popular series.
If you like character driven stuff, and Thor, perhaps you'd like Kieron Gillen's Thor run, or his even better Kid Loki book, Journey Into Mystery. I think they are collected in 'complete collections' now.
It's not a new series, I think it was cancelled last year, but I enjoyed Simon Spurrier's X-Men Legacy. It's about Legion, I character I had zero interest in, but I was sucked into the story and all the personalities that made up Legion. It's kind of weird, and got a frenetic British humor, which I love, but it may not appeal to everyone.
Spurrier also did a miniseries called X-Club, which I found hilarious, and is accessible without being knowledgeable about X-stuff. There's a review here:
http://everydayislikewednesday.blogs...ew-x-club.html
And a panel from that review.