The Incredible Hulk #1 May 1962
The first appearance and origin of the Incredible Hulk in "The Coming of the Hulk."
It's the height of the Cold War and the government is about to test their new Gamma Bomb. Unfortunately, a carefree and oblivious teenager named Rick Jones wanders out onto the test area. Dr. Bruce Banner, the creator of the Gamma Bomb, rushes out to warn the young man away.
However, the bomb explodes and as Banner pushes the teenager to safety he is caught in the heart of a Gamma maelstrom. The gamma-rays that bombard Banner's taunt frame transform his physiology. Now, whenever Banner becomes angry he transforms into the man-brute known as the Incredible Hulk.
Feared by the public and hunted by the army, the Hulk becomes one of the most tragic figures in Marvel's history. General "Thunderbolt" Ross will not rest until the Hulk is destroyed. The creature's only allies are Rick Jones and Betty Ross, Thunderbolt's daughter and Banner's one true love. Thus begins the epic saga of the world's mightiest mortal.