MC2 Spider-Girl and Earth-X Spider-Girl are pretty big names too...
Than there's Spiderverse Spider-Girls/Women...
Mattie is dead, sure...
And Julia is Madam Web.
There's also Black Widow as she's named after a Spider.
I wouldn't really say those big names are around much anymore, though. And yes there will be Spider-Girl/Women in Spiderverse, but that's just an event. I'm talking just the mainstream universe.