Howard's been great post Secret Wars. The second issue was really great, and the first three issues have backup stories featuring Gwenpool. (They'll be collected in her first volume along with her holiday special as well, which you should look into.)
As far as I can tell Gwenpool is set in the Prime universe.
All we know of Loki's next series is that he's running for president and Angela is his bodyguard and that Sam Wilson is there as well. Should be a fun little six issue mini.