I voted Great Spider-Man Run.
The art in the run is absolutely fantastic. I actually really like the new origin stuff going on in the run. These comics were my introduction to Spider-Man in the 616 so nostalgia also plays a part in it. I would, honestly, love to see his take on the origin brought into the new Spider-Man films. I think it would be an interesting way to bring the origin back without having to retell it and do something different. Plus, Morlun would be a sick villain to do in these films.