As I've mentioned, he can essentially self-teleport across inter-galactic distances, so he is capable of quick movement.
Reaction-wise, he keeps up more or less evenly with a guy who is peak human+, but unless I am failing to remember something truly significant, they both are well below Spiderman level speeds/reactions.
I noticed what appears to be the unstoppable parasite on the Item list: Telepathic Parasite (DC: JLA/Hitman) 9
It's not even a 10, but 10 or not it shouldn't be on the list IMO.
They had a big discussion about it last league thread.
The MunchKING is Back! And he is AWSOME!
For a combo breaker, something One Piece for the distant future.
The Castle Castle Fruit is a pretty-bullshit-for-League-purposes Devil Fruit that turns the inside of your body into a castle which you can use to carry allies and weapons. You can open gates for these people to enter/leave the castle, or open weapons ports from the inside. Allies you carry are miniaturized inside your body, but resized to normal once they are a few inches outside you, and the same to attacks they happen to fire from inside you.
Man, that Oda, you'd think eventually he'd run out of ideas, but he just keeps coming up with crazier fruits!