Honestly, both Sam and Jane's number is probably going to be up within a year. Sam's storyline will crash into the next summer event if it's Captain America related (probably has to do with HydraSteve). Meanwhile Jane's cancer has to be dealt with at some point! Either she dies, or takes time off to get herself cured, either way she's done soon. Of course both are Avengers, so that book would get another shuffle too. It'd likely also lose Spider-Man (who funds the team), because of Parker Industries going up the swanny (a status quo change that's already been solicited), so don't expect the current Avengers volume to last any longer than ANAD Avengers did.