I just posted this on the "Gwenpool is getting an ongoing series" thread but seeing how this topic is also popping up I'll add my two cents here as well:
Gwen-Pool is in part a Alternate Gwen Stacy and yet also not any Gwen Stacy that we know of as well. She came from the Gwen Stacy June variant covers so she still has a link in that sense of comic origins plus looking at her and her body and face is that of Gwen Stacy but personality of Deadpool and some original styles and quirks of her own. I count her as a Alternate of Gwen and Deadpool composite in one yet still her own character.
The same applies in sense for Gwen Stacy/Spider-Gwen where she among a set of the many Gwen Stacys but also with the destiny and responsibility and trials of a alternate Spider hero. She's a "Gwen Stacy" yet like all Gwen Stacys have to be counted as their own character per world as a individual and not a perfect copy or have influence of the many possible outcomes, expectations, or exceptions as each fate is that of their own. Gwen Stacy of 616 and Gwen Stacy of 65 might be a Gwen and alternates of each other but different characters still with actions, environment, peers, and decisions who makes them who they are as individuals.
Gwen Stacys who could be villains, Gwens who could be silly, Gwens who could be serous, Gwens who would like certain Gwens, and Gwens who would hate certain Gwens and it all based on many factors. Even in the Gwen Stacy Appreciation thread Gwen Stacy of 65 is talked about alot (for understandable reasons) thus each "Appreciation thread" instead of honoring one character is in fact now (due to the nature of many different earths/worlds and characters in them in comics) a Appreciation thread to many different characters with the Alternate worlds and it's characters tossed in. Thus in such threads we have to be careful and make sure we are stating which version we might be talking about (there are Gwens I dislike and Gwens I love and some Peter Parkers and proxies I like and some neutral about).
Thus for me Gwen Poole is still part:
Gwen Stacy proxy AU category
Deadpool proxy AU category
and her own being like all characters are.
I think that the Earth from the one with "Spider-Storm" that is full of characters that are in some form a mix of two characters we know from 616 would be the perfect world that Gwen-Pool came from being part Deadpool and Gwen Stacy herself (with more Gwen in her genetics). That earth could be the one Gwen-pool came from and was apart of till something happened and she was stuck on 616. Gwen-Pool has to now relearn others and take in a world full of people she knows but feels to her incomplete being only half of who she knew every time and that change is jarring yet takes each one with stride. She feels like a joke KNOWING she is a joke, mixed, and "niche" character but wants to take whatever time she has to carve herself out and at least be entertaining and memorable in a good way for her readers with the limited time she knows she has and thus moves quickly, without thinking, and in the extreme for she could be canceled at any moment (self awareness is a big factor and also acknowledgment even with her own title being "Unbelievable" that she also can't believe she got a series for whatever time she has).
Hoping that the artist and writer is ready and has many great ideas and plots and character developments that we will enjoy making a quality and wonderful character and series.