Corny as I once thought it was, as I grow older I've grown to LOVE the idea of Lois as Superwoman, from the first golden age story where she acquired the powers to Grant Morrison's take on it in All Star. I LOVE Lois having those powers only for 24 hours at a time. I'm not saying I want to see it become a permanent thing--and by modern storytelling standards it's a bit hokey--but I just find a certain retro charm in the concept.
No interest in Jimmy as Elastic Lad or Lana as Insect Queen--but I'd go for Lois with Kryptonian powers for a day.