Jim Sterling recently did a look at Resident Evil 4 and why he loves the game a lot. Where it appeals more to comedy/horror at times and why the lead character is unlike what had came before. And after as Capcom pretty much fucked his character up. As he'd say cheesy one liners and hit very badly on women. As Sterling claims , "Its like they wanted to make a Metal Gear Solid game and had someone who knew he wasn't as cool as Solid Snake."
But Sterling as he points out in this claims he loved Resident Evil 4 the most.