If we assume the Beyonders did create the 616 in total at the beginning, and, Franklyn has the powers of the Beyonders, then it's possible the ANAD is as real as the 616 ever was. Then the only concern becomes, how does the ANAD develope without Reed and the FF? Also, Franklin did recreate what he thought was the heroes in Heroes Reborn, and they were nothing like the originals. Somehow, he has got closer this time in the ANAD, but who knows how close?