Slight error here: Father Rudolpho Boschelli is/was a priest running a church in Chicago, and was stuck raising child Domino after her mother Beatrice dumped her on the porch (after having freed her from a Project Armageddon facility before her planned liquidation). While there's a connection between the two it isn't biological/genetic.
Beatrice (last name unknown) was Caucasian, or at least looked it, but Domino's birth father - likely a donor - was never revealed, plus her chalk-white complexion was present from birth. So her true ethnicity remains up in the air (and not helped at all by more than a few '90s appearances that heavily leaned toward presenting her as Asian).