My unpopular, or perhaps popular since I think it's pretty sensible but I can never know with these forums, is that if I was in MU I'd 100% support mutants being registered in some government database. Their identities shouldn't be made public but at least at some level it should be known who is a mutant and who is not. That way if an accident involving a mutant happens, whether through voluntary use of powers or not, the source of the problem will be more easily identifiable. If it is an individual with malicious intent then prison, if not then he/she/they should be helped with their powers so it doesn't happen again. However comics usually go to the extreme and rather than having a nuanced take we have comically caricaturized hateful bigots sending death robots and whole government agencies hunting down mutants. And yes, I know we have comically caricaturized hateful bigots in real life too but it seems in MU there is no middle point between the recent CotA and the likes of William Stryker.
Edit: I really liked Gillen's 6 human characters in Judgment Day since those showed varying views on mutants ranging from sympathy to indifference to hate.