I don't want her to lost her intelligent, but to lose control as she becomes angrier? FOR SURE.
I prefer Rucka's version of a beast who once was (and maybe deepdown still is) a decent human. So then the lines get blurred and the character provides great tension. How many "villains who wants to turn people into beasts" we had before? How many ferocious ladies who want to kill?
But hey, a friend who is a victim because of her curiosity and becomes an animal, but doesn't lose herself completely? Who is killing to survive, who has a great reason to be angry, but still have to be stopped? Someone that we never know if is a victim still or likes who she is (Curiosity killed the cat, but satisfaction brought it back)? That I'm interested in seeing.