Originally Posted by
Quiver
This is, effectively, the reason why increased diversity needs to exist. The default assumption of a character shouldn't be "white, straight, cismale".
Heck, even with Peter it isn't. He has parallel universe counter parts who are British punks, Indian, ninjas, even a pig. It's clear that the Marvel multiverse can throw oit characters who are different from their mainstream counterparts.
Case in point. An old Exiles book featured a Mary Jane who was in a gay relationship...whereas 616!MJ hasn't expressed any such tendencies.
Alternatively... Collosus, as you pointed out, had his sexuality adapted for the Ultimate universe. There was a Wolverine featured in Extreme X-men, who was in a relationship with Hercules.
So, it is more than possible that a gay Peter Parker exists in the multiverse; it's a certainty.