This is a real review. I got the book early because I work in a comic book store, and I just finished it.
I'm on my phone, and don't know how to use the spoiler stuff, so I'll give you a chance to avoid spoilers if you want to read it.
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Okay, if you're still here, then you either 1) don't care or 2) also work in a CB store, lol.
Anyways...
SPOILERS GALORE, YO.
1) Yup, Madrox is dead, and the double page spread we see him in... is ghastly, to say the least.
2) The art is pretty damn good, especially the colors.
3) Hydra makes an appearance, because "Hail Hydra.".
4) There's no animosity between Cyke, Bobby, and Beast, so I'm assuming everyone is on, at least, decent terms following the "Hickman Kills Everyone" event.
5) Only the Inhumans see any action here, while it's all discovery for the Mutants/X-Men.
6) You can see why Magik would join Storm, because, for some reason, she doesn't see the mist/cloud as the Inhumans' fault. Weird.
7) The issue is designed to purposely show the very drastically different points of views both sides have when it comes to the cloud/mist. People who said that the previews made the Inhumans come off as creepy, or off, are right. There is an unsettling, yet subtle, arrogance that Crystal displays in her dialogue that, honestly, makes it hard to sympathize with the Inhuman side at all. The Inhuman kids come off as ignorant of the gravity of the situation, as the Royal family likes it (we saw them hide the fact that the mist killed Inferno's mother). Doesn’t help that the X-Men parts are generally colored darker, compared to the bright, and vibrant, In human parts. No offense to any religious people, but the Inhumans really come off as people blinded by faith here. Seeing their smiles, after seeing Madrox's painful, and horrific, death scene, was just...ugh.
8) While I think most of us could already surmise, this issue makes it clear that Cyke will die via the mist/cloud.
Overall, I'd give it an 7-7.5/10, because nothing really happened, and the ending dialogue for the X-Men side felt rushed. Cyke goes from saying that they need to be 100% sure before taking any action, to declaring war, and then Magik come off as being difficult for the sake of it. Her questioning Cyke blaming the Inhumans made NO SENSE. Of course it's the Inhumans' fault.
So yeah, if the point was to show both sides as equal (dat grey area), or show Cyke as being rash, then Marvel failed hard at that. However, taking it as it is, it was a good first issue.