As someone who just recently finished Spectacular Spider-Man, and LOVED IT SO MUCH, I would like to see a return to that kind of formula (although I have a feeling I might end up just wishing we get a Season 3 to Spectacular instead), but I think if they are going to do something different, an essentially "Spider-Men" show is an interesting idea with alot of potential.
I just hope this doesn't end up being "Every episode is travelling the multiverse" then that'll be tiring. If it's these Spider-characters (for the most part) in one location, I'm perfectly fine with.