Lex Luthor ("BvS")
Hector Hammond ("Green Lantern")
Aldrich Killian ("Iron Man 3")
Max Dillon/Electro ("ASM 2")
Victor Von Doom ("F4")
We've always had evil scientists as villains - the natural embodiment of our anxieties about scientific progress. (and an always marketable strain of anti-intellectualism) But lately they've gotten ... geekier. (less so with Doom, but he still applies - especially since he was originally a different evil archetype in the comics) Lizard in "ASM" was an evil scientist, but wasn't a geek so he's not on this list.
In addition to that, Killian, Hammond and Dillon all worshipped (auto-correct tells me "worshipped" has one "p" - does that seem right?) or at least admired the hero before becoming powered and turning to evil. What is that about? Some need to blame our heroes for creating the evils they fight? (i.e. Ultron) Is redemption now an intrinsic part of the new heroic narrative? (post Spider-Man perhaps?)