For good, just become a single dating dude. It's much better when Peter is always not tied down to relationships with pet wish fulfillment girlfriends of the author, you have to admit after omd, Peters been able to progress in narrative as far as being Spider-Man and progressing in his scientific potential, when he was married he was whipped and barely has time to improve himself as a hero and genius.
Being single is better for Peter imo, its a superhero action based comic after all and his love interests distract from exploring what peter is capable of as a hero and genius level character that no romance can hold a candle to. Plus peter is more than capable of doing better than the women peter has dated. But it shows marvel kicks them to the curb for some reason.