Imagine if Clark/Kal-El woke up one morning and found that while emotionally and mentally, he was his familiar self, his power set had been replaced by Doomsday's. In terms of durability/strength, the difference wouldn't be significant, and might even be slightly better, but he would have lost super senses, heat vision, X-Ray vision, sustained flight, etc. On the other hand, he now has crazy regenerative abilities and probably can't be killed permanently. Would this Superman with Doomsday's powers be more or less effective in his superheroic work than he would with his more familiar power set?
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