Ryan certainly has chops. He delivered a really powerful issue with this one
spoilers:end of spoilers
So it seems Billy Connors transformed himself into a Lizard and Curt needs the Regent tech in Normie's possession to cure him. Annie tags Curt with a Spider-Tracer and she and Peter later track the Lizards down to Oscorp, where they and Normie battle them. We learn Normie's heightened intelligence is due to him taking the goblin serum. After Annie saves Peter (twice in one issue), Normie gets emotional watching father and daughter bond, Peter swings away letting Normie know his father loved him. Normie blames Peter for ruining his birthday and clutches his father's photograph, crying. He angrily cries out to the heavens demanding why Peter didn't save his father, and plots revenge.
MJ was at the doctors', but she does appear in the flashbacks to Normie's family life.
It's revealed Harry's death from Spectacular Spider-Man#200 still occured in the RYV reality