Immortal hulk great power kinda tiein into spiderman one more day. The part where the hulk said you made everyone forget about who you are. Banner forget, but i don't forget. That is definitely a tie in. The writer acknowledge that comic. it means he was not affected by the effects of One More Day i.e. Mephisto saving Aunt May in exchange for wiping out all traces of Peter Parker and Mary Jane's relationship and marriage , it means Hulk and Mephisto are the only people who know that Peter Parker and Mary Jane were married and it shows how powerful Hulk's demon (TOBA) is confirming what Mephisto said previously. The continuity is excellent here, which is not always the case in modern comics.
IF they want a way to get Peter and MJW back, this is how they open the door. It would make for a fantastic story. There's great chemistry between Hulk/Banner and Spider-Man.